Southeast Missouri Vacation Packages
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Top Southeast Missouri vacation package deals
Price found within the past 48 hours. Click for updated prices.
4.0-star property
River City Casino & Hotel
9/10 Wonderful! (1,800 reviews)
Nov 3 - Nov 10
7 night stay
Burbank (BUR) to St. Louis (STL)
Southwest Airlines • Non-stop • Coach
St. Louis (STL) to Burbank (BUR)
American Airlines • Non-stop • Coach
Price was $999, price is now $796 per person
$796
per person
found 22 hours ago
Round are always clean
Good food and always pleasant staff
Reviewed on Sep 28, 2026
3.5-star property
The Wildwood Hotel
9.2/10 Wonderful! (1,672 reviews)
Nov 3 - Nov 10
7 night stay
Burbank (BUR) to St. Louis (STL)
Southwest Airlines • Non-stop • Coach
St. Louis (STL) to Burbank (BUR)
American Airlines • Non-stop • Coach
Save 100% on your flight
Price was $2,080, price is now $1,086 per person
$1,086
per person
found 22 hours ago
Clean friendly secure
Reviewed on Sep 28, 2026
3.0-star property
Residence Inn by Marriott St. Louis West County
9.2/10 Wonderful! (266 reviews)
Nov 3 - Nov 10
7 night stay
Burbank (BUR) to St. Louis (STL)
Southwest Airlines • Non-stop • Coach
St. Louis (STL) to Burbank (BUR)
American Airlines • Non-stop • Coach
Save 100% on your flight
Price was $1,538, price is now $947 per person
$947
per person
found 22 hours ago
Ive stayed here before. Rooms are nice because they have a desk kitchen snd couch. Bed was not good. We stayed here because our ac went out. I called and confirmed pet friendly booked and paid for the room only to arrive and be told its $100 pet fee. Thats not fair or ok.
Reviewed on Sep 4, 2026
4.0-star property
Moonrise Hotel
Delmar Loop
9/10 Wonderful! (2,026 reviews)
Nov 3 - Nov 10
7 night stay
Burbank (BUR) to St. Louis (STL)
Southwest Airlines • Non-stop • Coach
St. Louis (STL) to Burbank (BUR)
American Airlines • Non-stop • Coach
Price was $1,244, price is now $898 per person
$898
per person
found 22 hours ago
4.0-star property
The Cheshire
8.8/10 Excellent! (1,006 reviews)
Nov 3 - Nov 10
7 night stay
Burbank (BUR) to St. Louis (STL)
Southwest Airlines • Non-stop • Coach
St. Louis (STL) to Burbank (BUR)
American Airlines • Non-stop • Coach
Save 100% on your flight
Price was $1,491, price is now $1,112 per person
$1,112
per person
found 22 hours ago
Overall, I am glad that we only stayed at this property for one night. It is a property has great "hardware" - building, space, style (and potentially history and stories) but reall fell short on "soft" side as to service and management. No matter the lobby or our room, especially the carpert and bathroom, really left us a feeling of not clean. It is a pity that such a nice building and spacious place are not well maintained and well managed. The location of the property is also very nice with easy access to Forest Park. It can be better, much better.
Reviewed on Sep 29, 2026
Top rated hotels for your Southeast Missouri vacation package
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
46.88 mi from city center
$100 nightly
The price is $113 total per night
$113 total
Oct 4 - Oct 5
Total with taxes and fees
At Drury Plaza Hotel Cape Girardeau Conference Center, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and a conference center.
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
46.8 mi from city center
$72 nightly
The price is $81 total per night
$81 total
Oct 4 - Oct 5
Total with taxes and fees
Guests of Pear Tree Inn Cape Girardeau West enjoy free WiFi in public areas, a 24-hour business center, and a TV in a common area. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations.
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
Free Cancellation
Reserve now, pay when you stay
37.99 mi from city center
$57 nightly
The price is $62 total per night
$62 total
Oct 25 - Oct 26
Total with taxes and fees
Baymont Inn and Suites by Wyndham Farmington, MO features a 24-hour gym, free WiFi in public areas, and a conference center. There's free parking and an area shuttle. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and a computer station.
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Things to do
Night Ghost Tour of Pythian Castle in Springfield Missouri
$20
per adult
96% of travellers recommend
History Tour of Pythian Castle in Springfield Missouri
$13
per adult
90% of travellers recommend
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